MULTIPLEX IMMUNOFLUORESCENCE AND THE DIGITAL IMAGE ANALYSIS WORKFLOW FOR EVALUATION OF THE TUMOR IMMUNE ENVIRONMENT IN TRANSLATIONAL RESEARCH

Multiplex Immunofluorescence and the Digital Image Analysis Workflow for Evaluation of the Tumor Immune Environment in Translational Research

A robust understanding of the tumor immune environment has important implications for cancer diagnosis, prognosis, research, and immunotherapy.Traditionally, immunohistochemistry (IHC) has been regarded as the standard method for detecting proteins in situ, but this technique allows for the evaluation of only one cell marker per tissue sample at a

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Ventilator circuits mechanics and ventilator compensation

Introduction Invasive mechanical ventilation usually uses a double limb circuit.However, those circuits are not standardized and usually come from different manufacturers with different lengths, diameters, compliances and resistances.Those differences can affect the delivered tidal volumes and pressures delivered to the patient.We aimed to test thr

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